Clinical Trial Feasibility

Maximize
Recruitment ROI

Don’t risk inaccurate site and patient recruitment estimates. Our clinical trial feasibility services provide realistic, data-driven forecasts, patient-centric strategies, and early protocol optimization to keep you moving at the speed of science.

Feasibility, the Right Way

Effective clinical trial feasibility considers real-world site performance, competitive landscapes, and inherent start-up variability. Which is exactly what we do.

We use our global expertise and understanding of patient pathways to help you:

Avoid Overly Optimistic Projections

With real-world site performance data, feasibility analysis, and scenario planning we can set realistic expectations, model enrollment outcomes, and quickly address risks.

Stand Out From Competitors

We track active trials, locations, and eligibility criteria to refine site selection, improve recruitment strategies, and deliver realistic enrollment planning.

Make More Practical Eligibility Decisions

Highlighting protocol pressure points and providing actionable insights, we identify inclusion/exclusion criteria that may limit your patient pool and drive screen failures.

Assess Start-Up Readiness in Target Locations

We evaluate regulatory timelines, contracting complexities, supply chain, and import/export factors to build an optimized country activation path with clear risk mitigation strategies.

Faster Enrollment, Tighter Timelines, and
Stronger Execution for Smarter Trial Execution

What do you get when our clinical trial feasibility experts use real-world data, competitive intelligence, and regional insights to model scenarios, optimize site and country strategy, and build data-driven plans?

Make More Accurate Forecasts

We outline several scenarios for trial performance, screen failures and dropout rates, and create contingency plans to add sites/countries and adjust your study’s outreach.

Site Intelligence

We assess competing trials by geography, eligibility overlap, investigator priorities, and patient pathways to identify the very best investigators and sites.

Reduced Start-Up Risks

We pressure-test your site activation strategy by examining country-by-country activation dependencies and evaluating timeline assumptions so you can make more informed decisions.

Patient Pool Confidence

We triangulate epidemiology, real-world data, registry signals, and site intelligence, filling gaps where data are limited to support more accurate feasibility assessments and enrollment planning.

Clinical Trial Feasibility Services

Our feasibility insights deliver actionable decisions for your study and help reduce risk by preventing timeline slippage and avoiding common challenges, such as costly mid-study site or country additions, start-up delays, screen failures, and inaccurate population estimates.

Trial feasibility strategy and design input: We deliver global feasibility studies, scenario planning, and ongoing feasibility refresh during start-up and early enrollment
Site intelligence and investigator engagement: We provide site identification, site intelligence collection, and leverage regional experts and investigator/KOL relationships
Enrollment modeling and competitive landscape analysis: We review the competitive trial landscape using incidence, prevalence, and historical benchmarking
Patient pathway and recruitment strategy development: We provide patient pathway mapping, protocol validation/optimization to reduce burden, and alignment of recruitment and retention strategies
Eligibility and operational feasibility assessment: We evaluate inclusion/exclusion criteria, screen failure risk, country selection, and start-up readiness assessment
Patient insights and external data integration: We use surveys, forums, focus groups, advocacy groups, and broader clinical/medical expertise to inform strategy
Advanced recruitment enablement: We leverage recruitment vendors and AI tools to identify patient cohorts and hotspots, especially in rare and complex diseases
Holistic feasibility synthesis: We integrate epidemiology, competitive landscape data, and subject matter expert input to support decision-making and optimize trial design and execution

How Does Caidya Optimize Your
Clinical Trial Feasibility?

We’re invested in your success and proactively develop contingencies to keep you on track using our:

Trial feasibility experience from 145 engagements spanning Phase I-III
Regional-specific expertise that includes North America, Europe, and Asia-Pacific, with special expertise and presence in China
Therapeutic experience supporting feasibility in several areas, such as oncology, hematology, rare disease, cardio-metabolic, pediatrics, infectious disease, neurology, and several general medicine therapy areas

Frequently Asked Questions
About Clinical Trial Feasibility

How do you build enrollment projections that reflect real-world site performance?

Enrollment projections are built using historical site performance data, realistic recruitment rates, assumptions about screen failures, and scenario planning to reflect how sites perform in similar studies.

How do you account for competing trials targeting the same patient populations?

We analyze the competitive landscape by geography and site, including overlapping eligibility criteria and investigator prioritization, to adjust enrollment assumptions and identify high-risk competition areas.

How do restrictive inclusion/exclusion criteria affect feasibility and screen failure risk?

Tight criteria can significantly reduce the eligible patient pool and increase screen failure rates, which can slow enrollment, and may require protocol adjustments or mitigation strategies.

What feasibility inputs do you need when epidemiology or real-world data (RWD) are limited?

When data are limited, we triangulate available epidemiology, RWD, registry signals, site intelligence, and expert input to build more reliable population and enrollment assumptions.

How do you evaluate and recommend countries when start-up timelines vary widely?

Country selection considers regulatory and ethics timelines, contracting complexity, and operational readiness to build an optimized activation sequence with realistic start-up assumptions.

When should feasibility be refreshed after the initial assessment?

Feasibility should be continuously revisited during start-up and early enrollment to validate assumptions, adjust for real-world performance, and reduce downstream execution risk.

How do you shortlist sites when investigator workload and competing studies are high?

Site selection considers investigator capacity, competing trials, past performance, and recruitment potential to prioritize high-yield sites with the best likelihood of successful enrollment.

What are common feasibility “red flags” that drive mid-study rescue actions?

Common red flags include overestimated enrollment rates, high screen failure, underestimated competition, slow start-up, and poor site performance versus initial assumptions.

How do you balance scientific precision with operational feasibility in protocol planning?

We assess eligibility criteria and operational burden to identify trade-offs, ensuring protocols remain scientifically robust while still feasible for sites and patients.

What are the typical feasibility deliverables a sponsor receives?

Sponsors typically receive enrollment projections, site and country recommendations, competitive landscape analysis, screen failure risk assessment, and a comprehensive feasibility report to support decision-making.